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Nalbuphine HCL Nalbin 1ml Injection by Global Pharma 1 Amp

Nalbuphine HCL Nalbin 1ml Injection by Global Pharma 1 Amp

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Description

NALBIN 10&20 mg

(Nalbuphine HCL)

Composition:

Nalbupnins HCL…………………………….. 10 , 20 mg

Description:

Colorless ampule contains colorless transparent solution.

Indications:

Relief of moderate to severe pain, and as a supplement to balanced anesthesia/for preoperative and postoperative analgesia and for obstetrical labor and delivery.

Dosage and Administration;

The usual recommended adult dose is 10 mg / 70 kg individual, administered subcutaneously, intramuscular or intravenously this dose may be repeated every 3 to 6 hours as necessary. The recommended single maximum dose is 20 mg, with a maximum total daily dose of 160 mg. Doses should be adjusted according to the seventy of the pain and other medications which the patients may be receiving. As a supplement to balance anesthesia, induction doses range from 0.3 mg /kg to 3 mg / kg intravenously to be administered for 10 to 15 minutes period with maintenance doses of 0.25 to 0-50 mg / kg in single intravenous administration as required.

Patients Dependent on Narcotics:

Patients who have been taking narcotic chronically may experience withdrawal symptoms upon the administration of the drug. If unduly troublesome, narcotic withdrawal symptoms can be controlled by the slow intravenous administration of small increments of morphine until relief occurs. If the previous analgesic was morphine, pyrimidine, codeine, or other narcotic with similar duration of activity one-fourth of the anticipated doie of the drug can be administered initially and the patient observed for sign of withdrawal, i.e. Abdominal cramps, nausea and vomiting, incrimination, anxiety, restlessness, rhinorrhea, elevation of temperature or predilection. If untoward symptoms do not occur, progressively larger doses may be tried at appropriate intervals until the desired level of analgesia is obtained with the drug.

Precautions:

Nalbin injection should be administered with caution on the following cases:

1 ) Ambulatory patients who perform potentially dangerous task such as driving a car or operating machinery.

2) Emergency Procedures.

3) During labor and delivery.

4) Head Injury and increased intra cranial pressure.

5) When the drug is administered in combination with other central nervous system depressants.

6) Patients with respiratory depression, uremia, bronchial asthma. Cyanosis or respiratory obstructions.

7) Patients with hepatic, renal dysfunction or myocardial infarction.

8) Patients with nausea and vomiting.

9) Patients about to undergo surgery of the bacillary tract.

10) It is not advisable to administer Nalbin Injection to patients underage of 18.

11) Nalbin Injection may cause psychological and physical dependence- Therefore, patients should be closely supervised when long term therapy is contemplated.

Abrupt discontinuation of the drug following prolonged use has been followed by symptoms of narcotic withdrawal, i.e. Abdominal cramps, nausea and vomiting, rhinorrhea, ‘acrimation, anxiety, restlessness, elevation of temperature or piloerection, thereby the dose of the drug should be reduced slowly.

Use in Pregnancy:

Safety of the drug in pregnant women has not been established, thereby it should be administered to pregnant women or women who are at risk of being pregnant, when judged potential benefit Justified potential risk. Side Effects:

  1. Generally Nalbin may cause sedation, sweating, nausea vomiting, vertigo, dizziness, dry mouth, headache etc.
  2. CNS-Nen/ousness, depression, restlessness, crying, euphoria, floating, hostility, unusual dreams, confusion, faintness, hallucination, dysphoria, feeling of heaviness, numbness, tingling, unreality.
  3. Cardiovascular- Hypertension hypo tension, bradycardia, tachycardia.
  4. Gastro-intestinal – Cramps, dyspepsia bitter taste.
  5. Respiratory – Depression, dyspepsia asthma.
  6. Dermatologist! – itching burning, urticaria.
  7. Miscellaneous – speech difficulty, urinary urgency, blurred vision, flushing and warmth feeling.

Drug Interaction:

Patients receiving a narcotic analgesic general anesthetics, phenothlazine, or other tranquilizers, sedatives, hypnotics, or other CNS depressants concomitantly with the drug may exhibit an additive effect, thereby when such combined therapy is contemplated, the dose of one or both agents should be reduced-Contraindications:

Nalbin Injection is contraindicated in patients known to have a hypersensitivity to the drug

Storage Condition: Well-closed containers.

Presentation:

Nalbin Injection 10 mg  1 x 10’s Nalbin Injection 20mg  1 x 10’s.

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